Epidemiology and factors associated with Extra-pulmonary tuberculosis in a Low-prevalence area.

Background: Tuberculosis is a global public health problem. Extra-pulmonary tuberculosis accounts for an increasing proportion of cases worldwide, although information about epidemiological, clinical, or microbiological factors is lacking. Methods: We conducted a retrospective observational study of tuberculosis cases diagnosed between 2016 and 2021, classified into Pulmonary and Extra-pulmonary tuberculosis. Univariable and multivariable logistic regression models were used to investigate risk factors of Extra-pulmonary tuberculosis. Results: 20.9% of overall cases were classified as Extra-pulmonary tuberculosis, with a rising trend from 22.6% in 2016 to 27.9% in 2021. Lymphatic tuberculosis accounted for 50.6% of cases, followed by pleural tuberculosis (24.1%). 55.4% of cases belonged to foreign-born patients. Microbiological culture tested positive in 92.8% of Extra-pulmonary cases. Logistic regression analysis showed that women were more predisposed to develop Extra-pulmonary tuberculosis (aOR 2.46, 95% CI 1.45-4.20) as well as elderly patients (aged ≥ 65 years) (aOR 2.47, 95% CI 1.19-5.13) and persons with previous history of tuberculosis (4.99, 95% CI 1.40-17.82). Conclusions: Extra-pulmonary Tuberculosis have increased within our study period. A profound decline occurred in 2021 tuberculosis cases, probably due to COVID-19. Women, elderly population, and persons with previous history of tuberculosis are at higher risk of developing Extra-pulmonary tuberculosis in our setting.

Insights into a Community of Inquiry that emerged during academics' emergency remote university teaching of chemistry in response to concern for students

Background: Effective teaching of university chemistry in an online environment not only requires teachers to have specific discipline content knowledge;it also requires them to have knowledge and skills in technology-enhanced teaching practices. When transitioning from traditional face-to-face teaching into online contexts, teachers must learn new strategies and methods, along with a shift in their beliefs. Whilst online learning of chemistry is commonplace in many higher education institutions globally, the integration of computer and digital technologies in teaching chemistry in developing countries had been limited prior to the 2020 pandemic. Purpose: In this study, the experiences, perceptions, and teaching strategies of university chemistry teachers in the Philippines have been explored during the transition of their instruction to emergency remote teaching at two timepoints during the COVID-19 pandemic. Sample: Data were collected in the form of survey responses from 139 participants representing 35 universities and colleges across the nation. Results: No strong relationships were found between participants' experiences and their academic rank, length of service, or institution type, suggesting university chemistry teachers took similar approaches to quickly adopt and adapt available technologies to deliver the required curriculum. Since the Philippines continues to struggle to establish a robust infrastructure to promote online and technology-enhanced learning, participants had to devise pedagogies and practices that would allow accessible learning experiences for their students by curating online tools that would require minimal bandwidth and low internet data consumption. Using abductive methodology, the Community of Inquiry (CoI) framework was employed as a guide in interpreting university chemistry teachers' experiences and perceptions about their implementation of emergency remote teaching using online technologies. Whilst participants had limited prior experiences in employing online learning pedagogies, key elements of the CoI framework became apparent through the new technologies and practices implemented by university chemistry teachers which fostered teaching presence, cognitive presence, and social presence. © 2023 Crown Copyright.

Recuperacion laboral, clinica y funcional a 3 meses del alta en pacientes hospitalizados por neumonia por SARSCoV2. Relacion con la terapia recibida

Introduction: The SARS-CoV 2 pandemic has brought a high burden of disease. Its long-term repercussions are still under investigation. The objective of this report was to evaluate the occupational, clinical, and functional respiratory recovery at 3 months of patients hospitalized for COVID-19, related to the ventilatory therapy received. Material(s) and Method(s): Prospective cohort of 116 patients from the Hospital Naval Almirante Nef de Vina del Mar, Chile, with clinical and functional respiratory follow-up at 3 months. Result(s): Median follow-up 100 days. 75 men, Median age 60 years, 50% obese, 34.5% smokers and 13.8% with respiratory comorbidity. 16% had undergo rehabilitation. Dyspnea in 73.7% and fatigue in 50%. Only 54.8% returned to work. 65% who used oxygen therapy (O2) returned to work compared to 44% who used HFNC and 33.3% IMV. Return to normal life achieved was greater in the O2 group compared with HFNC group and IMV group (71.4% versus 17.5% and 11.1%). Pulmonary function tests were normal in 39 patients (33.6%). Normal DLCO and normal distance walked in 6 minutes were higher in the group that return to work. The HNFC group had an OR of 5.9 of DLCO alterations, while VMI group had an OR of 3.6 in relation to the group that received O2. Discussion(s): This cohort repeats risk factors and persistence of symptoms described in literature. DLCO alteration was the most frequently founding and to a greater extent than other reports. Conclusion(s): At 3 months of follow-up, work absenteeism, persistence of symptoms and respiratory functional alteration were frequently evidenced, especially in those who received ventilatory support.

Analysis of Survival in Patients with End-End Chronic Kidney Disease Switching from Peritoneal Dialysis to Hemodialysis Due to Refractory Peritonitis

Introduction: Peritonitis associated with peritoneal dialysis (PD) has complications such as transfer from PD to HD and increased morbidity and mortality. In our environment, there is little information regarding survival in this population. Method(s): Retrospective cohort, 147 PD patients, 18 years, with PD catheter removal between 2018-2021. Clinical, biochemical and technique-related variables were measured. Patients who died of cancer and other unrelated causes were excluded. Descriptive statistics, Kaplan-Mayer analysis and Cox regression analysis were used Results: Age 42 +- 17 years, 65% men, 65% unknown cause of CKD. The time between peritonitis diagnosis and catheter removal was 37 (25-61) days. Nine patients (6%) returned to PD, the rest (94%) remained on HD due to unfit abdomen (55%), patient decision (9%), unknown (17%), others (19%). Mortality was 31% and the causes of death were: sepsis (33%), COVID-19 (29%), pneumonia (19%), pulmonary edema (5%), hyperkalemia (5%), CVD (5%), others (4%). Survival after the refractory peritonitis event was 25 (95% CI 22-28) months. Survival at 3, 12, 24, and 36 months was 87%, 71%, 61%, and 35%. In the bivariate analysis, age, DM, time on dialysis, and serum albumin were associated with a higher risk of death. However, in the multivariate analysis, only time on dialysis was significant (OR 1.014, 95% CI 1.002-1.027). [Formula presented] Conclusion(s): Mortality was 31% and the most frequent cause of death was sepsis. Patient survival was 25 (95% CI 22-28) months. Time on dialysis was associated with a higher probability of death. It is necessary to compare these results with a group of patients who do not present failure of the technique. No conflict of interestCopyright © 2023

Real-world effectiveness of sotrovimab for the early treatment of COVID-19 in the US

The objective was to evaluate real-world effectiveness of sotrovimab, a monoclonal antibody (mAb) for the treatment of high-risk outpatients with COVID-19, in reducing the risk of mortality or hospitalization during the SARS-CoV-2 Delta and initial Omicron variant waves in the US. A retrospective analysis was conducted of de-identified, high-risk patients diagnosed with COVID-19 (index date) from 1 September 2021 to 28 February 2022 in the FAIR Health FH NPIC claims database. Patients were divided into 2 cohorts based on claimed procedural codes: treated with sotrovimab and not treated with any mAb (no mAb). Facility-reported mortality ("mortality"), all cause hospitalizations and intensive care unit (ICU) admissions <=30 days of index were identified. Multivariable logistic regression was conducted to estimate the risk of 30-day mortality or hospitalization, adjusting for demographic and clinical factors. Of the high-risk COVID-19 patients identified,13,140 were treated with sotrovimab and 1,283,284 received no mAb therapy. In the no mAb cohort, 0.59% died and 5.74% were hospitalized (of whom 30% in ICU). In the sotrovimab cohort, 0.08% died and 2.50% were hospitalized (of whom 15% in ICU). After adjusting for potential confounders, sotrovimab treatment was associated with 85% reduced odds of 30-day mortality (OR: 0.15, 95% CI: 0.08-0.31) and 61% reduced odds of 30-day hospitalization or mortality (OR: 0.39, 95% CI: 0.35-0.44) among high-risk COVID-19 patients. In this US real-world study of high-risk COVID-19 patients during the Delta and initial Omicron waves, treatment with sotrovimab was associated with reduced odds of mortality and hospitalization compared to no mAb treatment.

Validation of an instrument to measure teaching digital competencies in emerging non-contact environments from the perspective of the students

COVID-19 generated a transition from face-to-face educational settings to non-face-to-face ones. To adapt, teachers required digital skills (TDC). However, this transition brought with it uncertainty about the degree of development that teachers would have of these competencies. In this research, rather than taking a frame of reference that would allow identifying the TDC that a teacher required in pre-pandemic conditions, we worked on the design and validation of an instrument to assess the level of TDC displayed by teachers during the pandemic. To carry out the validation, a variation of the Delphi Method was used, which was called the Simplified Digital Delphi method (MDDS), in which a group of 27 experts participated in a virtual context. The results show that the instrument has high levels of validity since each item and category exceeded a V-Aiken coefficient of 0.8, and a confidence interval value (ICI) of 0.6, so it can be applied for the purpose to the one that was designed. © 2022 Authors. All rights reserved.

COVID-19 fever induced dynamic Brugada electrocardiogram

We present an interesting case and images of a patient with identified as having Brugada syndrome due to dynamic electrocardiographic (ECG) changes seen during high-grade fever in the context of an associated COVID-19 infection. We show serial ECGs demonstrating dynamic but unusual change from a Brugada Type-1 to a non-Type-1 Brugada pattern, then ultimately having ECG normalisation once the fever had been corrected with antipyretic medication. This case and set of images illustrate how ECG was helpful in successfully identifying a COVID-19 patient with underlying Brugada syndrome, thus enabling simple but appropriate management and risk-stratification. © 2022 Carlito Seroje Reyes et al.

Real-world Effectiveness of Sotrovimab for the Early Treatment of COVID-19 in the US

Background. Sotrovimab, a monoclonal antibody (mAb), received Emergency Use Authorization (EUA) for the treatment of high-risk outpatients with symptomatic COVID-19. The study objective was to evaluate real-world effectiveness of sotrovimab (500 mg intravenous) in reducing the risk of mortality or hospitalization during the SARS-CoV-2 Delta and initial Omicron variant waves in the US. Methods. A retrospective analysis was conducted of de-identified patients (pts) diagnosed with COVID-19 (ICD-10: U07.1) from 9/1/2021 to 2/28/2022 in the FAIR Health FH NPIC claims database. Pts were divided into 2 cohorts based on HCPCS codes: treated with sotrovimab and not treated with any mAb (no mAb). Pts meeting EUA high-risk criteria were identified via pre-specified ICD-10-CM diagnoses in records <= 24 months prior to their first COVID-19 diagnosis (index date). Facility-reported mortality (referred to as 'mortality'), all cause hospitalizations and intensive care unit (ICU) admissions within 30 days of index were identified. Chi-square test, ANOVA, or t-tests were performed to statistically compare cohorts at a 0.05 level of significance (2-sided). P-values were not adjusted for multiplicity. Multivariable logistic regression was conducted to estimate the risk of mortality or hospitalization within 30 days, adjusting for demographic and clinical factors. Results. Of the high-risk COVID-19 pts identified, 13,140 were treated with sotrovimab and 1,283,284 received no mAb therapy. Compared to the no mAb cohort, the sotrovimab cohort was older, had more baseline conditions, and were more likely to be female (all p < 0.0001). In the no mAb cohort, 0.59% died and 5.74% were hospitalized (of whom 30% in ICU). In the sotrovimab cohort, 0.08% died and 2.50% were hospitalized (of whom 15% in ICU). After adjusting for potential confounders, treatment with sotrovimab was associated with 83% reduced odds of 30-day mortality (OR: 0.17, 95% CI: 0.09-0.31) and 61% reduced odds of 30-day hospitalization or mortality (OR: 0.39, 95% CI: 0.35-0.43) among high-risk COVID-19 pts. Conclusion. In this US real-world observational study of high-risk COVID-19 pts during the Delta and initial Omicron waves, treatment with sotrovimab was associated with reduced odds of mortality and hospitalization compared to no mAb treatment.

Acalculous Cholecystitis: A Novel and Lethal Unrecognized Complication in Severe CoVID 19

Background. SARS-COV-2 infection is known to cause tissue damage in several organs outside of the respiratory tract. The pathogenesis of tissue damage is hypothesized to be caused by direct viral damage, endothelial injury, and ischemic or thrombotic events. Gastrointestinal symptoms were first characterized mainly as diarrhea and diffuse abdominal pain and discomfort, which can be hard to interpret in the setting of a generalized inflammatory response;gallbladder injury and inflammation causing acute acalculous cholecystitis has been scarcely reported Methods. Here we discuss five cases of patients presenting with symptoms of cholecystitis. All five patients underwent multiple imaging studies, and all of them were compatible with acute cholecystitis;some of them had an imaging report of lithiasic cholecystitis, while the rest were reported with microlithiasis or biliary sludge. Four out of the five patients underwent laparoscopic cholecystectomy;biopsies were taken, consistently those reported with acalculous cholecystitis. The remaining patient died of CoVID 19 complications prior to surgery, but after a percutaneous cholecystostomy tube was placed. Results. All these patients have in common the prolonged fasting, because they all required invasive mechanical ventilation, consequently, they all developed multiple focal pneumonia and respiratory distress syndrome. This fast is related to the development of gangrenous ischemia in the gallbladder, which manifests as a late complication due to SARS-CoV-2 infection, in addition to being related to angiotensin-2 converting receptors and virus replication proteins, as well as the pro-inflammatory and hypoxia state that in itself causes the infection (9). All showed a cholestatic pattern, highlighting that this complication developed in an average time of 3 weeks after the onset of SARS-CoV2 symptoms, in addition to the fact that in most cases a negative test was already shown at the time of the complication. Conclusion. Acalculous cholecystitis is one of the extrapulmonary complications that has been seen in patients with this infection, not being the most common, but one of those that has generated a higher mortality rate in patients due to its late diagnosis and non-specific clinical picture in certain occasions (9).

Psychiatric Treatment of the Medically Complex Patient: An Overview of the Primary Psychiatric Service on a Medical/Surgical Unit

In most hospitals in the United States, inpatient psychiatric units are not equipped to accommodate medically complex patients. To address this problem, Kern Medical hospital in Bakersfield, California implemented the primary psychiatry service (PPS) that is complementary to the 24-bed psychiatric unit and the psychiatric consultation and liaison service. PPS facilitates care to patients who meet criteria for inpatient psychiatric hospitalization but are not eligible for admission to the inpatient psychiatric unit due to medical requirements. With PPS, patients are admitted to the medical/surgical floor under primary management of the consultation liaison psychiatry team. Additional care is provided by medical/surgical nursing staff previously trained by the psychiatry department, attending psychiatrist, psychiatry residents, and consulting physicians. A protocol for admission includes patients on a legal psychiatric hold or under voluntary psychiatric hospitalization who also have concurrent acute psychiatric and chronic medical conditions that are not suitable for the inpatient psychiatric unit. Primary psychiatry admission is approved by the attending psychiatrist and insurance. Some of the funding for patients admitted to PPS is provided by Kern County's Behavioral Health and Recovery Services through the Mental Health Services Act. As a result of this service, Kern Medical admitted 49 patients to PPS in 2021. The main diagnoses of primary-psychiatric-eligible patients were mood disorders, psychotic disorders, and disorders related to substance use. The most common medical conditions requiring admission to PPS were for impaired ambulation and COVID-19 infection requiring isolation. Additional data will be included in the poster. The primary psychiatric service has been helpful with providing acute psychiatric care to medically compromised patients and has facilitated the flow of psychiatric patients within the emergency department. Being able to finance such protocols can be challenging as well, but the benefits are innumerable. There are potential challenges that can arise in such systems, including issues with medical complications and potentially lengthy disposition. Overall, from our single center experience it has been quite positive. Whether this novel system can be replicated in other centers effectively would be an area for further evaluation. Learning Objectives: - Awareness of an alternative model of psychiatric care to the traditional inpatient psychiatric setting - List benefits and challenges to having a psychiatric primary service as part of the consultation liaison service - Identify key patient diagnoses that one may encounter from psychiatric primary service References: Hussain M, Seitz D. Integrated models of care for medical inpatientswith psychiatric disorders: a systematic review. Psychosomatics. 2014 Jul-Aug;55(4):315-325. Epub 2014 Apr 13. PMID: 24735866. Kathol RG, Kunkel EJ, Weiner JS, McCarron RM, Worley LL, Yates WR, Summergrad P, Huyse FJ. Psychiatrists for medically complex patients: bringing value at the physical health and mental health/substance-use disorder interface. Psychosomatics. 2009 Mar-Apr;50(2):93-107. PMID: 19377017. Copyright © 2022

Outcomes Among Hospitalized Patients With COVID-19 and AKI: Role of SARS-CoV-2 Vaccine

Background: COVID-19 and Acute kidney injury (AKI) are associated with increased mortality and worse kidney outcomes. Although vaccines against SARS-CoV-2 have decreased the rate COVID-19 morbimortality, the role of immune protection against SARS-CoV-2 in the setting of AKI has not been fully yielded Methods: Retrospective case-control study that included clinical and biochemical data of 412 (78 vaccinated and 334 non-vaccinated) patients with severe COVID-19. Cox regression analyses were used to evaluate the effect of the vaccine in mortality and AKI outcomes Results: The mean age of the patients was 55+/-15 years, 64% were women, the mean body mass index was 28+/-5 kg/m2, and median in-hospital stay was 10(6-16) days. The rate of mortality and AKI 3 was 29% vs 10% and 27% vs 13%, for unvaccinated and vaccinated patients, respectively. Cox proportional hazard ratios for survival and prevention of AKI are shown in table 1 Conclusion(s): The SARS-CoV-2 vaccine was independently associated with lower mortality and AKI progression in patients with severe COVID-19.

Digital gap in initial teacher training: challenges in learning environments during the COVID-19 pandemic in La Guajira (Colombia)

The primary goal of this study is to assess the opportunities that students have to access and handle digital training scenarios while displaying the skills needed to use information and communication technologies on a digital ecosystem. The methodological approach has a mixed design. A questionnaire containing 28 items is applied and an online discussion forum is set up. The sample consists of 280 students from the Faculty of Educational Sciences at the University of La Guajira (Colombia). The results indicate that there is a gap in access to technology, since only 45.7% of the participants claim to have a personal computer or a tablet, while only 39.3% can regularly access the Internet. It is concluded that during the COVID-19 pandemic there were considerable gaps in accessing and using digital tools;however, students developed skills to more efficiently use the technologies they had access to. © 2022,Formacion Universitaria. All Rights Reserved.

Preparation and reliability analysis of a questionnaire to measure, from the student’s perspective, the teacher’s digital skills in non-classroom teaching environments

During 2020, the pandemic caused by COVID-19 expanded in Latin America, as a consequence face-to-face teaching experienced an abrupt transition to non-face-to-face environments, some of them supported by technologies, especially by the use of platforms for the management of learning and learning. video conferencing sessions. This forced teachers more than ever to discover and deploy their technological skills, however, this transition brought with it uncertainty about the level of development of teachers’ digital skills. This article presents the elaboration and reliability analysis of an instrument called the Digital Competences Questionnaire in Non-Presential Environments (CD-NP), whose objective is to measure in a non-presential teaching environment the perspectives of high school students on skills. shown by their professors to implement the chair mediated by the use of digital tools. In the elaboration and validation of the questionnaire, 19 experts participated, who concluded that the basic digital competences required by teachers to respond to the new reality of teaching are: communicative interaction, the selection and design of digital materials, and the evaluation of learning. 392 students from a private university collaborated to carry out the reliability analysis. The findings show that the instrument has acceptable levels of reliability since various analyzes were carried out, the most representative being that each item and category exceeded a Cronbach’s alpha of 0.8093 and a McDonald’s Omega coefficient of 0.8958. It is concluded that the instrument has the necessary properties to be applied in the Mexican context, and opens the door to be implemented in other Latin American scenarios. © 2022, Universidad Compultense Madrid. All rights reserved.

Evaluation of a Virtual Campus Adapted to Web-Based Virtual Reality Spaces: Assessments of Teachers and Students

Educational institutions have continuously adapted to new realities in school education, accelerated recently by the COVID-19 pandemic's transformation of learning modalities. This article analyzes teachers' and Students' acceptance of a web-based virtual reality (WebVR) tool called Virtual Campus proposed to overcome the limitations of teaching strategies using video conferencing platforms. To measure the acceptance of the Virtual Campus, we designed an instrument based on the Technology Acceptance Model (TAM) that involves variables related to online contexts, the future perception of using the tool, skills development, and appreciation and recommendation. The results indicate that the participants favorably accepted WebVR technology as an alternative teaching methodology in emerging learning scenarios and intend to use it post-pandemic. The best-valued elements were interactions in the socialization spaces, the simulation of presence, and the environmental dynamics. The principal areas of opportunity for improvement were overcoming technical problems and improving the internet connection quality;however, these did not affect the participants' recommendations. Future studies should incorporate variables related to analyzing learning mediated by WebVR-based strategies and using different methodological designs to compare the findings.

Students' Experience Using a Web-based Virtual Reality Tool

The Covid-19 social distancing policies forced educational institutions to make significant changes. Schools had to migrate to a non-face-to-face modality using technological tools. However, using these communication platforms had negative consequences for students, such as concentration difficulties and feelings of isolation and anxiety. One alternative disruptive technology used to reduce these problems is virtual reality. This research aimed to know the users' experience with a Virtual Campus based on WebVR activities at a higher education institution in Mexico. The methodology applied was a qualitative case study. The results indicated satisfactory student experience, engaged participant interaction, dynamic activities, and socialization in an environment similar to face-to-face education. The main difficulties related to specific technical problems using the tool. However, these did not affect the positive assessment of the participants since 92.7% of the respondents would recommend a friend to use it. Future studies should include the teachers' perspective, design strategies that promote activities organized by students, and inclusion of others unrelated to academia.

Training and Educational Innovation: An Evaluative Perspective of the Digital Teaching Competence

This article analyzes the assessment of the four development levels of the Digital Teaching Competence (DTC) to recognize the needs and formulation of challenges in training and educational innovation required in the pedagogical practices of university professors under the current context of the Covid-19 pandemic. The study used an empirical-analytical methodology with a nonexperimental, transactional, descriptive design. The sample design was probabilistic, estimated with 95% confidence and 5% error among 252 teachers from various faculties of the University of La Guajira (Colombia). The selected instrument corresponded to the rubric's application to evaluate the university professor's digital teaching competence in Latin America. Among the study's significant results, we highlight that the rubric presented a high Cronbach's alpha reliability (α: 0.947). In the general assessment of DTC development, it was estimated that 78.2% of teachers are in the first two levels of DTC development assessment (Beginning and Middle). The evaluation rubric allows identifying challenges and opportunities that teacher training must address to advance the professional development of professors. © 2022, International Journal of Emerging Technologies in Learning. All Rights Reserved.

Long COVID in Cancer Patients: Preponderance of Symptoms in Majority of Patients over Long Time Period

Background. An increasing number of observational studies have reported the persistence of symptoms following recovery from acute COVID-19 disease. The long-term consequences of COVID-19 are not fully understood and there is no clear consensus on the definition of post-acute sequelae of SARS-CoV-2 infection (PASC). The reported prevalence of PASC widely varies from 10% up to 87%. The purpose of this study is to assess PASC in cancer patients following acute COVID-19 recovery. Methods. We assessed cancer patients at MD Anderson Cancer Center who were diagnosed with COVID-19 disease between March 1, 2020 and Sept 1, 2020. Using patient questionnaires and medical chart reviews we followed these patients from March 2020 till May 2021. Patient questionnaires were sent out remotely daily for 14 days after COVID-19 diagnosis then weekly for 3 months, and then monthly thereafter. Chart reviews were conducted for each patient hospital re-admission and emergency department visit. These admissions were classified as either COVID-19 related or non-related. The persistence or emergence of new COVID19-related symptoms were captured at each COVID-19 related admission. Results. We included 312 cancer patients with a median age of 57 years (18-86). The majority of patients had solid tumors (75%). Of the 312 patients, 188 (60%) reported long COVID-19 symptoms with a median duration of 7 months and up to 14 months after COVID-19 diagnosis. The most common symptoms reported included fatigue (82%), sleep disturbances (78%), myalgias (67%) and gastrointestinal symptoms (61%), followed by headache, altered smell or taste, dyspnea (47%) and cough (46%). A higher number of females reported a persistence of symptoms compared to males (63% vs 37%;p=0.036). Cancer type, neutropenia, lymphocytopenia, and hospital admission during acute COVID-19 disease were comparable in both groups and did not seem to contribute to a higher number of long-COVID-19 patients in our study group. Conclusion. Long-COVID occurs in 60% of cancer patients and may persist up to 14 months after acute illness. The most common symptoms are fatigue, sleep disturbance, myalgia and gastro-intestinal symptoms.